IS (Interact Series) - family of engines used for on-highway applications, trucks, buses and RVs
ISF 2.8-liter I4 - used in GAZ GAZelle (Business and Next series) and Foton Tunland light trucks
ISV 5.0-liter V8 - used in the 2016 and newer Nissan Titan XD truck, up to 2019 model-year[21]
ISB 5.9-liter I6, 190 HP - used in first, second, and third generation Ram 2500 and 3500 trucks until 2007
ISB 6.7-liter I6 - used in third and fourth generation Ram 2500-5500 trucks, medium duty trucks, such as Freightliner and International. Used in Kenworth and Peterbilt called the Paccar PX6 or PX7.
ISC 8.3-liter I6 - discontinued
ISL 8.9-liter - I6 - used for a variety of applications, and a very common engine for buses
ISL G 8.9-liter - I6 natural-gas-powered; used for a variety of applications
ISM 11-liter I6 - used for a variety of vocational applications in lesser regulated areas
ISG 12-liter I6 - used primarily in Chinese HD trucks
ISX 12-liter I6 - used in heavy-duty trucks
ISX G 12-liter I6 - natural-gas-powered; used in heavy-duty trucks
ISD 12.4-liter I6 - used in tractor applications in lesser regulated areas
ISX 15 liter I6 - used in heavy-duty trucks
V555 9.1-liter V8 - used in heavy machinery and large trucks[22]
V903 14.8-liter V8 - used in Bradley fighting vehicles and other military applications
QS (Quantum Series) - family of engines used for off-highway applications, such as marine, rail/industrial, construction, power generation and agriculture
QSF 2.8-liter I4
QSF 3.8-liter I4
QSB 4.5-liter I4
QSB 6.7-liter I6
QSL 9-liter I6
QSG 12-liter I6
QSX 15-liter I6
QSK 19-liter I6
QSK 23-liter I6
QST 30-liter V12
QSK 38-liter V12
QSK 45-liter V12
QSK 50-liter V16
QSK 60-liter V16
QSK 78-liter V18
QSK 95-liter V16
X Series (Next-Generation) - evolution of IS engine family
X12
X15 Performance 15-liter I6
X15 Efficiency 15-liter I6